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Testosterone and anabolic steroids have been found to affect the central nervous system in laboratory animals and humansalike. In the context of brain function, several studies have reported deficits in the regulation of cognition and executive function, and alterations in the functions of the serotonergic system. Many of the changes found to have been produced by the chronic abuse of these compounds have been related to the dopamine system. This review describes the literature related to the effects of low doses of testosterone and anabolic steroids on cognitive function and executive function. The impact of these compounds on cognition, an important facet of executive function, is outlined. Additionally, the effects of testosterone and anabolic steroids will be examined on several other aspects of brain function, including: blood-brain barrier (BBB) function, neurotoxicity, neurotransmission, and memory and learning. Related Article: